F. Fossati et al., RADIOFREQUENCY ABLATION OF THE SLOW PATHW AY IN RECIPROCATING NODAL RHYTHMS, Archives des maladies du coeur et des vaisseaux, 89(9), 1996, pp. 1159-1165
Radiofrequency ablation is a therapeutic alternative to drug therapy i
n recurrent reciprocating nodal rhythms. Selective ablation of the slo
w pathway guided by endocavitary recordings has the advantage of being
effective at the price of a very low incidence of atrioventricular bl
ock. The authors report their experience with this technique. Fifty co
nsecutive patients with recurrent attacks which were syncopal or uncon
trolled by medical therapy, underwent selective ablation of the slow p
athway, Firstly, they all underwent electrophysiological investigation
to confirm the nodal origin of the reciprocating rhythm before procee
ding to ablation itself, guided by the search for the slow pathway pot
entials. After ablation, it was impossible to trigger reciprocating ta
chycardia. Interruption of the anterograde slow pathway was achieved i
n 24 patients and of the retrograde pathway in 1 patient; the other 25
patients went on having dual conduction but with a prolongation of th
e effective refractory period of the slow pathway (268 +/- 46 ms vs 25
1 +/- 41 ms; p < 0.01). There were no cases of permanent complete atri
oventricular block. interruption of the slow pathway was associated wi
th shortening of the effective refractory period of the rapid pathway
(323 +/- 71 ms vs 348 +/- 80 ms; p < 0.01), which was not observed in
cases of persistent dual conduction. No recurrence of tachycardia was
observed during follow-up (mean period = 19.2 months);however, control
endocavitary studies in 25 asymptomatic patients after 1 to 3 months
showed recurrence in 4 cases, which led to immediate further radiofreq
uency ablation which was successful. The authors conclude that guided
selective radiofrequency of the slow intranodal pathway is a remarkabl
y effective and reliable method of treating poorly tolerated or resist
ant reciprocating nodal tachycardias. Widening of the clinical indicat
ions to patients not wishing to undergo long-term antiarrhythmic thera
py now possible.