Authors
Citation
M. Oukessou et al., PHARMACOKINETICS OF KETOPROFEN IN THE DONKEY (EQUUS-ASINUS), Journal of veterinary medicine. Series A, 43(7), 1996, pp. 423-426
Citations number
14
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
0931184X
Volume
43
Issue
7
Year of publication
1996
Pages
423 - 426
Database
ISI
SICI code
0931-184X(1996)43:7<423:POKITD>2.0.ZU;2-H
Abstract
The pharmacokinetic parameters of ketoprofen were determined in four d
onkeys after a single intravenous injection of a dose of 2.2 mg/kg bod
y weight. The total body clearance (Cl-B) was 414.0 +/- 98.70 ml/h/kg
(mean +/- SD), the volume of distribution at steady state (V-5S) 263.1
0 +/- 55.43 ml/kg and the elimination half-life 1.30 +/- 0.75 h. These
values were compared to those obtained in horses.