EFFECT OF A CARDIOSELECTIVE BETA-ADRENOBL OCKER BISOPROLOL ON 24-HOURBLOOD-PRESSURE PROFILE IN PATIENTS WITH MILD AND MODERATE HYPERTENSION

Authors
EPIPHANOVA ON OSCHEPKOVA EV ROGOSA AN NIKOLSKY VP ARABIDZE GG
Citation
On. Epiphanova et al., EFFECT OF A CARDIOSELECTIVE BETA-ADRENOBL OCKER BISOPROLOL ON 24-HOURBLOOD-PRESSURE PROFILE IN PATIENTS WITH MILD AND MODERATE HYPERTENSION, Kardiologia, 36(8), 1996, pp. 21-24
Citations number
12
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
Kardiologia → ACNP
ISSN journal
00229040
Volume
36
Issue
8
Year of publication
1996
Pages
21 - 24
Database
ISI
SICI code
0022-9040(1996)36:8<21:EOACBO>2.0.ZU;2-Q
Abstract
Effect of a cardioselective beta-adrenoblocker bisoprolol on 24-hour b lood pressure profile was studied in 14 men aged 45+/-2 years with mil d and moderate hypertension. Ambulatory 24-hour blood pressure monitor ing was performed after 2 weeks of placebo and 8 weeks of treatment wi th bisoprolol (10 mg once a day). Bisoprolol significantly decreased m ean systolic and diastolic blood pressure and indices of ''pressure bu rden'' both during day and night time, diminished blood pressure varia bility and improved characteristics of diurnal rhythm due to increase of day-night gradient.