How does a common action arise between researchers, industrialists and
legal experts when patents are filed ? This question is investigated
by looking at the controversies that have arisen around hybridoma tech
nology in bioindustry. Five issues are studied: the definition of a ba
sic technique, the notion of identical antibodies, the meaning of an o
bvious application, the persons recognized as experts, and the determi
nation of what is to be set down to natural properties or to human int
erventions. The work that changes hybridoma into an ''invention'' resu
lts from a construction that brings together science and law.