ALPRAZOLAM PREMEDICATION AND 35-PERCENT CARBON-DIOXIDE VULNERABILITY IN PANIC PATIENTS

Authors
POLS H VERBURG K HAUZER R MEIJER J GRIEZ E
Citation
H. Pols et al., ALPRAZOLAM PREMEDICATION AND 35-PERCENT CARBON-DIOXIDE VULNERABILITY IN PANIC PATIENTS, Biological psychiatry, 40(9), 1996, pp. 913-917
Citations number
17
Categorie Soggetti
Psychiatry
Journal title
Biological psychiatry → ACNP
ISSN journal
00063223
Volume
40
Issue
9
Year of publication
1996
Pages
913 - 917
Database
ISI
SICI code
0006-3223(1996)40:9<913:APA3CV>2.0.ZU;2-N
Abstract
A group of 20 patients who met the DSM-III-R criteria for panic disord er with or without agoraphobia underwent a 35% carbon dioxide (CO2) ch allenge after either 1 mg alprazolam or placebo in a double-blind, ran domized, cross-over design. Despite the anxiolytic potential of alpraz olam, it produced no significant effects on CO2-induced anxiety and pa nic symptomatology when compared to placebo. (C) 1996 Society of Biolo gical Psychiatry.