A four-staged operation is currently the most effective treatment avai
lable in the management of stable Graves' ophthalmopathy. This report
describes the results of four-staged therapy in 51 patients with Grave
s' ophthalmopathy. Stage I, orbital decompression: 58 orbits in 32 pat
ients underwent orbital decompression, with an average retroplacement
effect of 4.2 +/- 2.2 mm (mean +/- SD). This procedure is effective to
restore vision and correct the proptosis due to Graves' ophthalmopath
y. Careful intraoperative titration of the retroplacement effect durin
g orbital decompression is very important to active successful results
. Stage II, strabismus surgery: 24 patients underwent strabismus surge
ry, including 11 with previous decompression surgery and six with prev
ious simultaneous decompression and strabismus surgery. The overall su
ccess rate was 87% and previous decompression or strabismus surgery ha
d no influence on the final results. Stage III, fissure width adjustme
nt: 28 patients (45 eyes) received fissure width adjustment. Various p
rocedures were performed and we found Mullerectomy with levator muscle
stripping to be the most useful procedure for fissure width adjustmen
t. The average improvement of fissure height was 3.1 +/- 1.8 mm. The r
ate of overall satisfactory results was 89%. There were five patients
who received Staged IV cosmetic procedures with satisfactory results.
Graves' ophthalmopathy is a chronic disease that needs thorough cooper
ation between doctor and patient. Careful evaluation of clinical param
eters and individualized surgical goals are the keys to success.