ACRODERMATITIS CHRONICA ATROPHICANS IN AN 11-YEAR-OLD GIRL

We report a case of acrodermatitis chronica atrophicans in an 11-year- old girl living in an area endemic for Lyme borreliosis. The diagnosis was first made on the basis of clinical, histopathological and serolo gical findings, Moreover, Borrelia burgdorferi-specific DNA was amplif ied from lesional skin by polymerase chain reaction, Intravenous treat ment with ceftriaxone (2 g once daily) for 2 weeks was initiated, The skin changes clearly responded to the therapy, and Borrelia burgdorfer i-specific gene segments were no longer detectable by polymerase chain reaction. This is the first report of molecular-proven acrodermatitis chronica atrophicans in childhood, The occurrence of this late skin m anifestation of Lyme borreliosis in children is reviewed.