EPSTEIN-BARR VIRUS-ASSOCIATED GASTRIC-CARCINOMA

Epstein-Barr virus (EBV) is associated with certain types of gastric c arcinoma. We report a case of EBV-positive undifferentiated carcinoma of the stomach in a 59-year-old woman with a well-demarcated ulceratin g tumor in the gastric body. Examination of the resected stomach revea led that the tumor was undifferentiated carcinoma with lymphoid stroma , or lymphoepithelioma-like carcinoma. Tumor cells were positive for E BV by in situ hybridization. Gastroenterologists must keep in mind tha t localized ulcerating tumors of the stomach histologically seen as un differentiated carcinoma noma with lymphoid stroma are linked to EBV i nfection.