In Churug-Strauss Syndrome (CSS), gastrointestinal tract (GIT) is an u
ncommon site of involvement. In addition to review of recent literatur
e, we herein report a case of CSS with unusual involvement of GIT. The
patient was being treated for idiopathic hypereosinophilic syndrome f
or 2 years; he later developed acute peritonitis and an emergency lapa
rotomy revealed 3-cm-diameter perforation in the small intestine. In o
rder to establish a correlation between the clinical features and the
histopathological findings, we highlight the importance of adequate sa
mpling and examination oi mesenteric vessels in the attached mesentry
in the resected specimen.