ABNORMAL FETAL AORTIC VELOCITY WAVE-FORM AND MINOR NEUROLOGICAL DYSFUNCTION AT 7 YEARS OF AGE

Citation
D. Ley et al., ABNORMAL FETAL AORTIC VELOCITY WAVE-FORM AND MINOR NEUROLOGICAL DYSFUNCTION AT 7 YEARS OF AGE, Ultrasound in obstetrics & gynecology, 8(3), 1996, pp. 152-159
Citations number
33
Categorie Soggetti
Acoustics,"Obsetric & Gynecology","Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
09607692
Volume
8
Issue
3
Year of publication
1996
Pages
152 - 159
Database
ISI
SICI code
0960-7692(1996)8:3<152:AFAVWA>2.0.ZU;2-2
Abstract
Measurements of fetal aortic blood flow velocity and fetal growth were performed in 178 pregnancies. In 87 cases, the estimated fetal weight was greater than or equal to 2 SD below the gestational age-related m ean of the population. Three fetuses died in utero. In 149 children (8 5%), a neurological examination was performed at 7 years of age with s pecial emphasis on minor neurological dysfunction. The frequency of th e more severe form of minor neurological dysfunction, MND-2, was highe r in the group with blood flow class (BFC) III (absent or reversed end -diastolic flow velocity (8/21) than in the group with BFC 0 (normal v elocity waveform) (14/105). Logistic regression analysis revealed that abnormal blood flow class, both independently and in combination with other factors, was the most significant predictor of MND-2. The assoc iation found between abnormal fetal aortic velocity waveforms an adver se outcome in terms of minor neurological dysfunction suggests that he modynamic evaluation of the fetus has a predictive value regarding pos tnatal neurological development.