An improved method for computer-aided 3D reconstruction of neuroanatom
ical structures derived from intracranially fixed human brains is demo
nstrated. The embedded brains are cut into slices. The sliced surfaces
are photographed. The outlines of the neuroanatomical structures are
drawn onto transparencies which are scanned. The surfaces of the struc
tures are 3D reconstructed with the triangulation method. The cortical
structures of the human brain are complex, resulting in possible ambi
guities for triangulation which must be solved interactively. These su
rface reconstructions allow for 3D visualization of the brain and its
components comparable with intravital conditions found in clinical neu
roimaging. Copyright (C) 1996 Elsevier Science Ltd