B. Misset et al., SHORT-TERM IMPACT OF THE EUROPEAN CONSENSUS CONFERENCE ON THE USE OF SELECTIVE DECONTAMINATION OF THE DIGESTIVE-TRACT WITH ANTIBIOTICS IN ICU PATIENTS, Intensive care medicine, 22(9), 1996, pp. 981-984
Because it remained controversial, the use of selective digestive deco
ntamination (SDD) in patients in the intensive care unit (ICU) was cho
sen as the topic of the first European Consensus Conference in Intensi
ve Care Medicine (ECCICM) in December, 1991. The Consensus Bureau deci
ded to assess the impact of this conference 2 years afterwards, For th
is purpose, a questionnaire was sent to the members of the European So
ciety of Intensive Care Medicine, the Societe de Reanimation de Langue
Francaise and the Societe Francaise d'Anesthesie et Reanimation befor
e the conference, The recommendations following the conference discour
aged the systematic use of SDD in ventilated patients and urged the mo
nitoring of bacterial resistance and adapting antibiotics to epidemiol
ogy of the units, Two years after the conference, the same questionnai
re mras sent to those physicians who had responded to the first one, E
ighteen percent used SDD for all ventilated patients and 17% remain us
ers after 2 years. Among the occasional (32%) or continual (17%) users
of SDD, the regimens used were mostly intravenous cefotaxime (60% of
systemic antibiotics) and a topical combination of polymixin E, tobram
ycin, and amphotericin B (62% of overall topical combinations). The an
tibiotics used were unchanged after 2 years in almost all cases. In co
nclusion, the short-term impact of the Consensus Conference on SDD in
ICU patients has been poor. This map be related to the continuing insu
fficiency of strong, definite data regarding the impact of this techni
que upon mortality and the theoretical risk of resistance to antibioti
cs, thus allowing physicians to stick to their policies until there is
new evidence.