ONCHOCERCA-VOLVULUS - IDENTIFICATION OF CDNAS ENCODING A PUTATIVE PHOSPHATIDYL-ETHANOLAMINE-BINDING PROTEIN AND A PUTATIVE PARTIALLY PROCESSED MESSENGER-RNA PRECURSOR

We have identified and sequenced cDNAs of the parasitic nematode Oncho cerca volvulus which encode a homologue of phosphatidylethanolamine-bi nding proteins from mammals. These clones are also closely related to the O. volvubus Ov16 cDNA (Lobos et al., 1990). One identified cDNA cl one appears to represent a partially processed precursor. These result s suggest that these cDNAs are derived from a complex genomic locus, r aising the possibility of polycistronic transcription in this nematode .