DOMBROCK BLOOD-GROUP (DO) - ASSIGNMENT TO CHROMOSOME 12P

Authors
EIBERG H MOHR J
Citation
H. Eiberg et J. Mohr, DOMBROCK BLOOD-GROUP (DO) - ASSIGNMENT TO CHROMOSOME 12P, Human genetics, 98(5), 1996, pp. 518-521
Citations number
19
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
98
Issue
5
Year of publication
1996
Pages
518 - 521
Database
ISI
SICI code
0340-6717(1996)98:5<518:DB(-AT>2.0.ZU;2-Q
Abstract
The Dombrock blood group system (DO) is a common polymorphism in Cauca sians, represented by two red cell antigen alleles. In a linkage study in our family material of 832 families from the Copenhagen area, we f ound a strong indication of tight linkage with the two flanking DNA po lymorphisms D12S358 (z = 7.66; at theta(M) = 0.001, theta(F) = 0.031) and D12S364 (z = 8.53; at theta(M) = 0.068, theta(F) = 0.031), DO is a ssigned to the region 12p13.2-12p12.1 by physically localised markers.