Winter Stress Syndrome (WSS) is a condition of severe lipid depletion
in fish brought on by external stressors in combination with normal re
ductions in feeding and activity during cold weather. Fish can develop
this syndrome in response to chemical stressors such as water polluta
nts, or biological stressors such as parasites. Substantial mortality
can result, potentially changing year-class strength and population st
ructure of the affected species, and altering community-level 'ecologi
cal interactions. Aquatic contaminants should be evaluated in the cont
ext of seasonal metabolic changes that normally occur in test organism
s. WSS could be an important, but as yet unquantified, cause of mortal
ity in many circumstances. Wastewater discharges may pose a greater to
xic threat to fish during winter than at other times of the year. A co
mprehensive protocol for aquatic hazard assessment should include test
ing for WSS. Published by Elsevier Science Ltd