Nearby supernova explosions may cause geological isotope anomalies via
the direct deposition of debris or by cosmic-ray spallation in the Ea
rth's atmosphere. We estimate the mass of material deposited terrestri
ally by these two mechanisms, showing the dependence on the supernova
distance. A number of radioactive isotopes are identified as possible
diagnostic tools, such as Be-10, Al-26, Cl-36, Mn-53, Fe-60, and Ni-59
, as well as the longer-lived I-129, Sm-146, and Pu-244. We discuss wh
ether the 35 and 60 kyr old Be-10 anomalies observed in the Vostok Ant
arctic ice cores could be due to supernova explosions. Combining our e
stimates for matter deposition with results of recent nucleosynthesis
yields, we calculate the expected signal from nearby supernovae using
ice cores back to O(300) kyr ago, and we discuss using deep-ocean sedi
ments back to several hundred Myr. In particular, we examine the prosp
ects for identifying isotope anomalies due to the Geminga supernova ex
plosion, and signatures of the possibility that supernovae might have
caused one or more biological mass extinctions.