OXYGEN NUCLEOPHILE INITIATED TANDEM CONJUGATE ADDITION-REACTIONS OF 1-NITRO-1-CYCLOHEXENE WITH 4-HYDROXY-2-BUTYNOATES - SYNTHESIS OF OCTAHYDROBENZO[B]FURANS
T. Yakura et al., OXYGEN NUCLEOPHILE INITIATED TANDEM CONJUGATE ADDITION-REACTIONS OF 1-NITRO-1-CYCLOHEXENE WITH 4-HYDROXY-2-BUTYNOATES - SYNTHESIS OF OCTAHYDROBENZO[B]FURANS, Synlett, (10), 1996, pp. 985
Treatment of 1-nitro-1-cyclohexene with methyl 4-hydroxy-2-butynoate i
n the presence of potassium tert-butoxide gave 3a-nitrooctahydrobenzo[
b]furan in excellent yield through a tandem conjugate addition initiat
ed by the oxygen nucleophile.