THE EFFECT OF SUBSTITUENTS ON THE FEASIBILITY OF [1,3]-PROTON SHIFT REACTION - NEW SYNTHETIC OPPORTUNITIES

Authors
SOLOSHONOK VA ONO T
Citation
Va. Soloshonok et T. Ono, THE EFFECT OF SUBSTITUENTS ON THE FEASIBILITY OF [1,3]-PROTON SHIFT REACTION - NEW SYNTHETIC OPPORTUNITIES, Synlett, (9), 1996, pp. 919
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
9
Year of publication
1996
Database
ISI
SICI code
0936-5214(1996):9<919:TEOSOT>2.0.ZU;2-P
Abstract
The effect of substituents on the feasibility of biomimetic [1,3]-prot on shift isomerization of the imines derived from benzyl trifluorometh yl ketone has been studied. Reaction rate was shown to be controlled b y the nature of substitution on the N-site of starting imine. Specific ally, the electron-withdrawing substituent on the phenyl of N-benzyl g roup facilitates the azomethine-azomethine isomerization.