S. Okumura et al., PULMONARY RESECTION FOR METASTATIC COLORECTAL-CANCER - EXPERIENCES WITH 159 PATIENTS, Journal of thoracic and cardiovascular surgery, 112(4), 1996, pp. 867-874
We reviewed the clinical courses of 159 patients between February 1967
and May 1995 for the purpose of examining the survival of patients wh
o had pulmonary resection for metastatic colorectal cancer. The cumula
tive survivals at 5 years and 10 years were 40,5% and 27.7%, respectiv
ely, Fifteen patients (10%) were alive more than 10 years after the th
oracotomy without any evidence of recurrence, The cumulative survival
at 5 years for 39 patients who had hepatic metastases before thoracoto
my was 33%, There was a statistically significant difference in surviv
al between patients with extrapulmonary metastases and those with only
intrapulmonary metastases before thoracotomy, The number of pulmonary
metastases and the presence of hilar or mediastinal lymph node metast
ases affected postthoracotomy survival, There was no significant diffe
rence in survival on the basis of sex, age, location of the primary ca
ncer, size of the pulmonary tumors, mode of operation, or disease-free
interval, Surgical treatment for pulmonary metastases from colorectal
cancer in selected patients, even those who had hepatic metastases be
fore thoracotomy, might improve prognosis.