Klippel-Trenaunay syndrome is a triad of cutaneous hemangiomas, varico
se veins, and hypertrophy of soft tissue and bone; when combined with
arteriovenous fistulas, the syndrome is known as Klippel-Trenaunay-Web
er syndrome. Orthopaedic surgical management of localized limb-length
discrepancy or hypertrophy in these conditions is frequently indicated
, especially in the lower limb. Forty orthopaedic procedures in 21 pat
ients were retrospectively reviewed. Nine (22.5%) wound complications
were identified in this study group. All the complications were associ
ated with transverse amputations. All required significant further tre
atment and extension of hospital stay. Wound complications should be a
nticipated in patients with Klippel-Trenaunay syndrome having orthopae
dic surgical procedures, especially terminal amputations.