I. Sharma et al., HYPOLIPEMIC AND ANTIATHEROSCLEROTIC EFFECTS OF ZINGIBER-OFFICINALE INCHOLESTEROL-FED RABBITS, PTR. Phytotherapy research, 10(6), 1996, pp. 517-518
Hyperlipidaemic rabbits when challenged with a 50% EtOH extract of Zin
giber officinale showed a reduction in total cholesterol and serum LDL
-cholesterol, A reduction in HDL ratio was seen in atherofed rabbits c
ompared with controls which were restored when challenged with the Zin
giber extract. An atherogenic index of 4.7 was brought down to 1.2 usi
ng plant products. The tissue lipid profiles of liver, heart and aorta
showed similar changes to those noticed in serum lipids, Zingiber ext
ract feeding increased the faecal excretion of cholesterol thus sugges
ting a modulation of absorption.