Rd. Sharma et al., TOXICOLOGICAL EVALUATION OF FENUGREEK SEEDS - A LONG-TERM FEEDING EXPERIMENT IN DIABETIC-PATIENTS, PTR. Phytotherapy research, 10(6), 1996, pp. 519-520
Toxicological evaluation of fenugreek seeds was made in 60 NIDDM subje
cts in a 24 week study in which changes in body weight, clinical signs
and symptoms and serum parameters such as SGOT, SGPT, alkaline phosph
atase, bilirubin, creatinine and blood urea, together with haematologi
cal parameters, was studied. ingestion of an experimental diet contain
ing 25 g fenugreek seed powder resulted in no renal or hepatic toxicit
y, but interestingly blood urea levels were seen to decrease after wee
k 12.