We developed a new resection device-the Rotoresect-with the aim of red
ucing morbidity during transurethral resection of the prostate (TURF),
During rotoresection, a rotating ablator electrode enables simultaneo
us tissue coagulation by high-frequency current and mechanical tissue
ablation, The tissue ablation rate and the extent of bleeding were qua
ntified ex vivo using a blood-perfused porcine kidney (N = 30) and the
n compared with loop resection and electrovaporization (grooved roller
/Rollerball), Additionally, transurethral rotoresection of the prostat
e and open partial resection of the liver were carried out in five dog
s, With the blood-perfused porcine kidney, we demonstrated that the ti
ssue ablation rate increases with increasing of the coagulation curren
t and rotation speed of the ablator electrode, The Rotoresect achieved
a tissue ablation rate comparable to that of the resection loop (5.5-
6.0 g/min), which was more than twice the rate achieved by electrovapo
rization (1.7-2.0 g/min), The extent of bleeding during standard loop
resection was many times higher (16.5-18.0 g/min) than that induced by
rotoresection and electrovaporization (<2.3 g/min), In our in vivo ca
nine trials, we performed transurethral prostate resection and open se
gmental liver resection with minimal bleeding, The Rotoresect is a pro
mising instrument for ablation of parenchymal organs during transureth
ral, laparoscopic, and open surgical procedures.