NONTYPABLE HAEMOPHILUS-INFLUENZAE SUSCEPTIBILITY - EFFECT OF INOCULUMSIZE AND BETA-LACTAMASE PRODUCTION

Authors
GOULD JM HEIDECKER GJ LIPUMA JJ
Citation
Jm. Gould et al., NONTYPABLE HAEMOPHILUS-INFLUENZAE SUSCEPTIBILITY - EFFECT OF INOCULUMSIZE AND BETA-LACTAMASE PRODUCTION, Diagnostic microbiology and infectious disease, 26(2), 1996, pp. 95-98
Citations number
13
Categorie Soggetti
Microbiology,"Infectious Diseases
Journal title
Diagnostic microbiology and infectious disease → ACNP
ISSN journal
07328893
Volume
26
Issue
2
Year of publication
1996
Pages
95 - 98
Database
ISI
SICI code
0732-8893(1996)26:2<95:NHS-EO>2.0.ZU;2-3
Abstract
The activities of cefixime, cefpodoxime, cefprozil, cefuroxime, loraca rbef, and amoxicillin/clavulanate against 72 clinical isolates of nont ypeable Haemophilus influenzae were determined by using an agar diluti on method. The effects of beta-lactamase production and bacterial inoc ulum size were investigated. Ail antimicrobials exhibited a significan t inoculum effect, demonstrating the importance of accurately determin ing inoculum size in the performance of antimicrobial susceptibility t esting of H. influenzae. (C) 1996 Elsevier Science Inc.