We report a 64-year-old Japanese man with oculo-neuroborreliosis. His
clinical features consisted of polyarthralgia, keratoconjunctivitis, c
horioretinitis. optic neuritis, confusion, and polyradiculitis. Assay
of antibodies to Borrelia species detected IgG-antibody to B. garinii
in both serum and CSF. Progressive declining of serum IgG antibody tit
er against Borrelia garinii, in parallel with clinical improvement, wa
s observed after administration of ceftriaxone.