CLATHRAMIDES, UNIQUE BROMOPYRROLE ALKALOIDS FROM THE CARIBBEAN SPONGEAGELAS CLATHRODES

Authors
CAFIERI F FATTORUSSO E MANGONI A TAGLIALATELASCAFATI O
Citation
F. Cafieri et al., CLATHRAMIDES, UNIQUE BROMOPYRROLE ALKALOIDS FROM THE CARIBBEAN SPONGEAGELAS CLATHRODES, Tetrahedron, 52(43), 1996, pp. 13713-13720
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
43
Year of publication
1996
Pages
13713 - 13720
Database
ISI
SICI code
0040-4020(1996)52:43<13713:CUBAFT>2.0.ZU;2-4
Abstract
Clathramide A (1a) and B (1b) are two novel isomeric bromopyrrole alka loids containing the uncommon N-methylimidazolinium moiety, isolated f rom the Caribbean sponge Agelas clathrodes. Their structures, elucidat ed on the basis of a detailed spectroscopic analysis, appear not biosy nthetically related to oroidin and its derivatives. In addition, 1a-1b exhibited a mild antifungal activity tested in an agar disk assay on Aspergillus niger. Copyright (C) 1996 Elsevier Science Ltd