DESIGN, SYNTHESIS, RESOLUTION, AND APPLICATION OF A HIGHLY EFFICIENT CHIRAL AUXILIARY - CIS-2-AMINO-3,3-DIMETHYL-1-INDANOL

Authors
SUDO A SAIGO K
Citation
A. Sudo et K. Saigo, DESIGN, SYNTHESIS, RESOLUTION, AND APPLICATION OF A HIGHLY EFFICIENT CHIRAL AUXILIARY - CIS-2-AMINO-3,3-DIMETHYL-1-INDANOL, Tetrahedron : asymmetry, 7(10), 1996, pp. 2939-2956
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
10
Year of publication
1996
Pages
2939 - 2956
Database
ISI
SICI code
0957-4166(1996)7:10<2939:DSRAAO>2.0.ZU;2-E
Abstract
The chiral amino alcohol, cis-2-amino-3,3-dimethyl-1-indanol was synth esized and resolved. Its oxazolidinone derivative was found to be a hi ghly efficient chiral auxiliary in diastereoselective alkylation, acyl ation, bromination, and hydroxylation reactions. Copyright (C) 1996 El sevier Science Ltd