Although liposarcoma is one of the most common soft-tissue sarcomas, f
acial localization is extremely rare, The buccal fat pad is an importa
nt anatomic structure located in the face that recently gained interes
t as a result of increasing research on facial anatomy, In this paper,
we report a case of giant liposarcoma originating from the buccal fat
pad, The precise localization of the tumor was determined preoperativ
ely with computed tomography examination. The liposarcoma that invaded
the body and the extensions of the buccal fat pad was resected comple
tely, The pathological examination revealed a sclerosing, well-differe
ntiated liposarcoma, which is known to be very rare in the head and ne
ck region, Chemotherapy and radiotherapy were not necessary because of
the favorable histological type of the tumor and the advanced age and
poor general condition of the patient, Local recurrence and distant m
etastasis were not observed during the 1-year follow-up.