We have developed a World Wide Web (WWW) version of the sequence retri
eval system Query: WWW-Query. This server allows to query nucleotide s
equence banks in the EMBL/GenBank/DDBJ formats and protein sequence ba
nks in the NBRF/PIR format. WWW-Query includes all the features of the
on-line sequence browsers already available: possibility to build com
plex queries, integration of cross-references with different data bank
s, and access to the functional zones of biological interest. It also
provides original services not available elsewhere: introduction of th
e notion of re-usable sequence lists, integration of dedicated helper
applications for visualizing alignments and phylogenetic trees and lin
ks with multivariate methods for studying codon usage or for complemen
ting phylogenies.