HOMOGENEOUS ASYMMETRIC HYDROGENATION OF O-CHLOROACETOPHENONE TO ENANTIOMERICALLY PURE O-CHLORO-(1-PHENYL)ETHANOL CATALYZED BY BINAP-RU(II) COMPLEX

Authors
RANE VH TAS D PARTON RF JACOBS PA
Citation
Vh. Rane et al., HOMOGENEOUS ASYMMETRIC HYDROGENATION OF O-CHLOROACETOPHENONE TO ENANTIOMERICALLY PURE O-CHLORO-(1-PHENYL)ETHANOL CATALYZED BY BINAP-RU(II) COMPLEX, Catalysis letters, 41(1-2), 1996, pp. 111-112
Citations number
7
Categorie Soggetti
Chemistry Physical
Journal title
Catalysis letters → ACNP
ISSN journal
1011372X
Volume
41
Issue
1-2
Year of publication
1996
Pages
111 - 112
Database
ISI
SICI code
1011-372X(1996)41:1-2<111:HAHOOT>2.0.ZU;2-I
Abstract
The BINAP-Ru(II) catalyst osphino)-1,1'-binaphthyl)chloro(p-cymene)rut henium chloride is found to be highly active and enantioselective for homogeneous asymmetric hydrogenation of o-chloroacetophenone to optica lly pure o-chloro-(1-phenyl)ethanol. In contrast to results of Noyori and coworkers, no organic and inorganic bases are required to obtain h igh activities and enantioselectivities.