FISH IMMUNOLOGY, THE UTILITY OF IMMORTALIZED LYMPHOID-CELLS - A MINI REVIEW

Long term cell lines can be readily established at high frequency with PBLs from normal channel catfish. Depending upon the mode of stimulat ion, morphologically and functionally distinct catfish lymphoid cell l ines resembling B cells, T cells and monocytes have been developed, Th ese fish cell lines appear unique from their putative mammalian counte rparts in that they are immortalized without the need for exogenous fa ctors or overt attempts at transformation.