Lw. Clem et al., FISH IMMUNOLOGY, THE UTILITY OF IMMORTALIZED LYMPHOID-CELLS - A MINI REVIEW, Veterinary immunology and immunopathology, 54(1-4), 1996, pp. 137-144
Long term cell lines can be readily established at high frequency with
PBLs from normal channel catfish. Depending upon the mode of stimulat
ion, morphologically and functionally distinct catfish lymphoid cell l
ines resembling B cells, T cells and monocytes have been developed, Th
ese fish cell lines appear unique from their putative mammalian counte
rparts in that they are immortalized without the need for exogenous fa
ctors or overt attempts at transformation.