EXPERIENCE WITH A PAPAVERINE PHENTOLAMINE /PROSTAGLANDIN E1-MIXTURE IN NONRESPONDERS TO AUTOINJECTION THERAPY/

In 75 patients with erectile dysfunction and insufficient treatment by papaverine/phentolamine and prostaglandin E1(PGE1), a papaverine/phen tolamine/PGE1 mixture was tested. 43/75 (57%) of the patients obtained erections sufficient for sexual intercourse. 22/43 (39.5%) began an a utoinjection program. In a clinical control after 12 months, 9/22 (41% ) had dropped out (2/17 spontaneous remissions, 1 cavernous fibrosis w ith extreme penile deviation). 13 patients carried out the therapy wit hout complications, but in 5 cases additional use of external erection al aids (vaccuum pump, erection ring) was necessary, Papaverine/phento lamine/PGE1 mixture is a successful additional diagnostic and therapeu tic tool in the treatment of erectile dysfunction for a smaller group of the patients.