J. Steffens et U. Humke, NECESSITY OF BLOOD-PRESSURE CONTROL IN CH ILDREN WITH SUCCESSFUL CORRECTION OF VESICORENAL REFLUX, Aktuelle Urologie, 27(5), 1996, pp. 314-316
Renal hypertension represents the most common form of secondary hypert
ension in childhood. The main cause is reflux nephropathy. With a mean
follow-up of 17 years, 859 children were investigated after successfu
l correction of vesicorenal reflux. Renal scars were found in 25.3% pr
eoperatively. During the observation period there was an increase in r
enal scarring of up to 30.5%. In 10.5% of the patients with renal scar
s, arterial hypertension occurred between 12 acid 14 years postoperati
vely and was found in 8% of the patients with unilateral reflux nephro
pathy, but in 14.5% of those with bilateral reflux nephropathy. Childr
en without scars developed no rise in blood pressure. Hypertension is
a complication even of successfully corrected vesicorenal reflux. Rena
l scarring was found to be an essential precondition for renal hyperte
nsion. Therefore blood pressure should be controlled annually on a lon
gterm basis throughout childhood and puberty, even after the child has
left pediatric care, because there is also a late manifestation of hy
pertension, In case of unilateral reflux nephropathy, toss of renal fu
nction and significant renal vein renin ratio, blood pressure can be n
ormalized by nephrectomy.