PREPARATIONS OF 1-HYDROXYINDOLE DERIVATIVES AND THEIR POTENT INHIBITORY ACTIVITIES ON PLATELET-AGGREGATION

Authors
SOMEI M YAMADA K HASEGAWA M TABATA M NAGAHAMA Y MORIKAWA H YAMADA F
Citation
M. Somei et al., PREPARATIONS OF 1-HYDROXYINDOLE DERIVATIVES AND THEIR POTENT INHIBITORY ACTIVITIES ON PLATELET-AGGREGATION, Heterocycles, 43(9), 1996, pp. 1855-1858
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
9
Year of publication
1996
Pages
1855 - 1858
Database
ISI
SICI code
0385-5414(1996)43:9<1855:PO1DAT>2.0.ZU;2-L
Abstract
1-Hydroxymelatonin, 5-bromo- and 5,7-dibromo-1-hydroxytryptamine deriv atives, 1,4-dihydroxy-5-nitroindole, 1-hydroxy-3-methylsulfinylmethyli ndole, and 4,5-tetrahydro-1-hydroxypyrrolo[4,3,2-de]quinoline were syn thesized for the first time, 1-Hydroxyindoles revealed potent inhibito ry activities on platelet aggregation.