ADJUVANT INTRAOPERATIVE RADIATION-THERAPY (IORT) FOR GASTRIC-CANCER

In order to evaluate the role of adjuvant IORT in the treatment of res ectable gastric carcinoma, we carried out a randomized trial comparing surgery and surgery + adjuvant IORT. The study included 115 patients within a 74-month period, 51 of them received a single application of 28 Gy to the celiac axis. Patients were comparable with regard to age, sex, tumor stage and operative morbidity. The difference in mean surv ival time (IORT: 26.9 months vs. non-IORT: 30.8 months) and tumor-rela ted death in the longterm course (mean follow-up period 29.2 months) w ith 29.4% (15/51) in the IORT-treated patients vs. 31.2% (20/64) in no n-irradiated patients did not reach significance.