A MILD PREPARATION OF 2,6-PIPERIDINEDIONES

Authors
ZHU JR CHUONG PH LEMOINE P TOMAS A GALONS H
Citation
Jr. Zhu et al., A MILD PREPARATION OF 2,6-PIPERIDINEDIONES, Heterocycles, 43(9), 1996, pp. 1923-1926
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
9
Year of publication
1996
Pages
1923 - 1926
Database
ISI
SICI code
0385-5414(1996)43:9<1923:AMPO2>2.0.ZU;2-Q
Abstract
Substituted glutaric acids reacted with alkyloxyamines in the presence of N-ethyl-N-dimethylaminopropylcarbodiimide hydrochloride to form 1- alkyloxy-2,6-piperidinediones. The protecting group on the nitrogen wa s easily removed in high yield. This process is exemplified by the pre paration of aminoglutethimide.