In the present study, 195 patients, following total gastrectomy (n = 1
05) or subtotal gastric resection (n = 90) for carcinoma without evide
nce of recurrence, were examined with regard to their quality of life
using the Gastrointestinal Quality-of-Life Index (GLQI). After subtota
l gastric resection patients achieved statistically significant better
scores concerning disease-therapy-related symptoms and physical funct
ions, resulting in a better overall score (p < 0.02). However, it seem
s to be questionable whether these statistically significant differenc
es are of clinical relevance in the patient's daily life. Preservation
of the gastric stump with the aim of improving postoperative quality
of life should never be allowed to compromise oncological radicality.