MOTOR NEUROPATHIES MIMICKING AMYOTROPHIC-LATERAL-SCLEROSIS MOTOR-NEURON DISEASE

We report three patients in whom the initial diagnosis was of possible Amyotrophic lateral sclerosis (ALS/MND) according to the 'El Escorial Criteria'. AU of them presented with monomelic paresis, atrophy of th e paretic muscles and generalised brisk reflexes. The initial electrom yograms showed a neurogenic pattern in the limbs with normal sensory a nd motor conduction velocities. Laboratory evaluation and imagiologica l investigations were normal in all of them. The previous diagnosis wa s changed in to demyelinating motor neuropathy with conduction block i n 2 patients and tomaculous neuropathy in one after clinical and elect romyographic follow-up and nerve biopsy. Patients 1 and 2 were given i ntravenous immunoglobulin treatment and showed moderate improvement.