The aortic pressure (AoP) and pulmonary artery pressure (PAP) are impo
rtant factors for the longterm survival of the patient receiving an im
plant of a total artificial heart (TAH). A new afterload regulation me
thod using neural controllers has been developed for a moving actuator
type TAH. Without any transducer, the proposed neural controller, bas
ed on the predetermined peak level of the motor current, regulates AoP
by adjusting the actuator velocity. At the same time, a fuzzy control
ler based on expert knowledge prevents the PAP from being abnormally h
igh. The proposed controller not only regulates the pump output on the
maintenance of the normal AoP and PAP, but it also successfully contr
ols the suction in the right heart. In vitro tests show that the propo
sed neural and fuzzy controllers effectively regulate AoP and PAP as w
ell as prevent atrial suction.