ALS is a progressive degenerative neuromuscular disease for which ther
e is no known cause, treatment, or cure. The steady disease progressio
n of muscle weakness eventually causes paralysis, disabling the patien
t. Day-to-day patient care and management most frequently fall to fami
ly members. The resultant financial burden can be enormous. We review
financial issues related to the diagnosis, management of disease progr
ession, and issues of life support. Cost-effective solutions are discu
ssed. It is believed the key to reduction of costs is education of the
health care community, patients and families, and third-party payers.