Aortic dissection most often is an acute event dominated by excruciati
ng pain and other symptoms which Suggest the diagnosis. Our report and
a review of the medical literature demonstrate that chronic aortic di
ssection may, rarely, present as a prolonged febrile illness, with nig
ht sweats, weight loss, pleural effusion, and little or no pain. These
symptoms may be associated with a markedly elevated erythrocyte sedim
entation rate (ESR), anemia of chronic disease, and hyerglobulinemia.
Awareness of this unusual presentation, a high index of suspicion, and
confirmation by an appropriate imaging technique (CT or MRI of the ch
est or transesophageal echocardiography have a very high sensitivity)
will result in earlier diagnosis and better patient outcome.