Sl. Hempel et De. Elliott, CHEST PAIN IN AN ASPIRIN-SENSITIVE ASTHMATIC PATIENT - EOSINOPHILIC ESOPHAGITIS CAUSING ESOPHAGEAL DYSMOTILITY, Chest, 110(4), 1996, pp. 1117-1120
We describe a case of eosinophilic esophagitis in a 38-year-old man wi
th aspirin-sensitivity asthma which presented as noncardiac chest pain
. Manometric measurements demonstrated tertiary contractions. Biopsies
showed a dense eosinophilic infiltrate in the mucosa. There was no re
sponse to therapy for reflux. Symptoms quickly resolved with corticost
eroid therapy. Subsequent manometric values recorded after corticoster
oid therapy showed resolution of the dysmotility. Biopsies showed norm
al mucosa. Adult asthmatic subjects with noncardiac chest pain should
receive further investigation if reflux therapy fails to resolve the s
ymptoms.