APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS .17. SYNTHESIS OF AZAISOINDOLO[2,1-A]QUINOLINE DERIVATIVES

Authors
EPSZTAJN J GRZELAK R JOZWIAK A
Citation
J. Epsztajn et al., APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS .17. SYNTHESIS OF AZAISOINDOLO[2,1-A]QUINOLINE DERIVATIVES, Synthesis, (10), 1996, pp. 1212
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
10
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):10<1212:AOOARR>2.0.ZU;2-2
Abstract
The synthesis of the 3-hydroxy-5(or 7)-azaisoindolin-1-ones and their conversion into 2-aryl-2,3-dihydro-3-oxo-1H-azaisoindole-1-acetic acid s, and their subsequent cyclization via sequential treatment with oxal yl chloride and aluminium chloride as a way of regiospecific transform ation of pyridinecarboxylic acids into the corresponding dihydroazaiso indolo[2,1-a]quinolinediones is described.