Although tobacco smoking is known to result in coronary heart disease,
chronic obstructive pulmonary disease, peripheral vascular disease, c
erebrovascular disease, lung cancer, and other smoking cancers, many s
urgeons believe that smoking also results in impaired wound healing an
d poor surgical results. Large clinical experiences in several areas o
f plastic surgery reinforce this suspicion. Procedures that have been
noted to be adversely affected by cigarette smoking include rhytidecto
my, abdominoplasty, breast reconstruction, free-tissue transfer, and d
igital replantation. This article reviews the available data, introduc
es new clinical data, and hypothesizes about the ways in which some pr
ocedures are more affected than others.