ONE-POT FACILE SYNTHESIS OF SOME NEW 9,10-DIHYDROACRIDINE DERIVATIVES

A convenient one pot synthesis of 9,10-dihydroacridine derivatives 3a- f and 4a-d has been described by the condensation of N-methylaniline o r 5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one with appropriate aroma tic adehydes (1) and 5,5-dimethyicyclohexane-1,3-dione (2) in methanol . These final products can alternatively be obtained from bis-dimedony l derivatives (5) and 2-arylidene-5,5-dimethylcyclohexane-1,3-dione (6 ) on reaction with N-methylaniline or 5,5-dimethyl-3-benzylamino-2-cyc lohexen-1-one and suggest the key steps to reaction mechanism.