MEASUREMENT OF 3,4-DIHYDROXYPHENYL ETHYLENE-GLYCOL (DOPEG) IN PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION

Authors
CANNMOISAN C CAROFF J LEBRAS P GIRIN E CURET O GANDON JM
Citation
C. Cannmoisan et al., MEASUREMENT OF 3,4-DIHYDROXYPHENYL ETHYLENE-GLYCOL (DOPEG) IN PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION, Journal of liquid chromatography & related technologies, 19(19), 1996, pp. 3119-3124
Citations number
8
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of liquid chromatography & related technologies → ACNP
ISSN journal
10826076
Volume
19
Issue
19
Year of publication
1996
Pages
3119 - 3124
Database
ISI
SICI code
1082-6076(1996)19:19<3119:MO3E(I>2.0.ZU;2-R
Abstract
Usually, determination of DOPEG in plasma by EC-HPLC is always perform ed after extraction on alumina. This paper presents an extraction on b oric acid gel, with good selectivity,, reproducibility. In high sensit ivity conditions (0.5 nA full scale) an autosampler is used and presen ts two major advantages: first, the possibility of storing samples in cold conditions to preserve stability of DOPEG, second the analysis of numerous samples in pharmacological studies, for example.