Kr. Harkin et al., ASSOCIATION OF PERIANAL FISTULA AND COLITIS IN THE GERMAN-SHEPHERD DOG - RESPONSE TO HIGH-DOSE PREDNISONE AND DIETARY THERAPY, The Journal of the American Animal Hospital Association, 32(6), 1996, pp. 515-520
Twenty-seven German shepherd dogs with perianal fistulas and histologi
cal evidence of colitis were entered in a prospective clinical study t
o investigate the association between perianal fistula and colitis. Ad
ditionally, the response of perianal fistula disease to immunosuppress
ive doses of prednisone and an alternative protein diet was evaluated
All 27 cases completed the treatment protocol, and perianal fistulas c
ompletely resolved in nine (33.3%) cases, improved in nine cases, and
remained unchanged in nine cases.