C. Laugel et al., SIMILAR QUALITATIVE AND QUANTITATIVE O W/O AND W/O EMULSIONS - IMPROVEMENT OF COSMETIC PROPERTIES/, STP pharma sciences, 6(5), 1996, pp. 376-380
The aim of this study was to compare o/w/o multiple emulsions with w/o
simple emulsions in terms of occlusivity and remanence. Firstly, four
teen o/w/w multiple emulsions were prepared with w/o emulsion componen
ts. Several parameters were optimized i.e. primary emulsion/multiple e
mulsion ratio, concentration of the emulsifiers, mixing speed. The yie
ld and stability of the preparation were measured by a tracer release
method using phthalic acid diethyl ester. This tracer, introduced in t
he inner oily phase, was chosen according to general requirements : a
high oil/water diffusion coefficient, good stability under various pH
and temperature,and easy detection. From entrapment yield and droplet
breakdown curves calculated from the tracer UV spectrophotometric data
, one emulsion was selected for comparison with the w/o emulsion. Skin
oil level measurements with a sebumeter provided efficient data to ev
aluate the remanence. Occlusivity was measured by the gravimetric meth
od of water loss with gelatin cells. The remanence improved significan
tly, since the occlusivity properties were retained. As the total perc
entage of oil was the same within the two emulsions, the increase of r
emanence is mainly due to the galenic form.