NOVEL TECHNIQUES FOR THE OFF-LINE ANALYSIS OF LIQUID PROCESS STREAMS BY MASS-SPECTROMETRY

Two novel methods for the analysis of simulated liquid process streams are described; static headspace analysis-MS and total vaporization-MS . A variety of experimental parameters have been studied and optimized for the detection of acetone and methyl iodide in water and acetic ac id matrices, respectively, The detection limits (3 sigma) for the head space technique at a sample temperature of 71 degrees C are 0.5 and 2 mu g ml(-1) and for the total vaporization technique are 19 and 1 mu g ml(-1), respectively, for acetone and methyl iodide, The RSD for conc entrations of 10 mu g ml(-1) of the above analytes are generally less than 6% [n = 6 (static headspace method), n = 10 (total vaporization m ethod)].