DIAPHYSEAL TELANGIECTATIC OSTEOSARCOMA AS A 2ND TUMOR AFTER BILATERALRETINOBLASTOMAS

In this report, we describe the clinical, imaging, and pathologic find ings in a case of diaphyseal telangiectatic osteosarcoma arising 23 ye ars after successful treatment of bilateral retinoblastomas. To our kn owledge, telangiectatic osteosarcoma occurring as a second tumor in th is setting, outside the radiation treatment field, has not been previo usly reported. The association of the RB-1 gene defect with retinoblas tomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma ar e described and discussed.